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Discoid Lupus

Is an inflammatory scarring alopecia. It is an autoimmune condition and a type of chronic skin lupus. It presents as a sharply-demarcated red, scaly plaque with a central depressed scar, central skin lightening, follicle scale plug, and a surrounding dark patch. It occurs 4-5 times more common in black women compared to white women. Systemic lupus erythematosus (SLE) may develop in 5-25% of people with DLE. It may be associated with other autoimmune conditions and increased risk for squamous cell carcinoma. Management includes the use of sun protection, anti-inflammatory medications (i.e. steroids (topical/ oral/ injection), tacrolimus, methotrexate, etc.)
References:
- Gro¨nhagen CM et al. Increased risk of cancer among 3663 patients with cutaneous lupus erythematosus: a Swedish nationwide cohort study. Br J Dermatol 2012;166:1053e9.
- Jessop S et al. Drugs for discoid lupus erythematosus. Cochrane Database Syst Rev. 2017 May 5;5:CD002954.
- McDaniel B, Tanner LS. Lupus Erythematosus, Discoid. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018 Jan 2018 Sep 26.
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